Degradation of Nuclear Factor Kappa B during Foot-and-Mouth Disease Virus Infection

Lyophilizing Foot-and Mouth Disease Virus at Low Drying Temperature

Foot-and-mouth disease virus.

Foot-and-mouth disease virus (FMDV) is an aphthovirus of the family Picornaviridae and the etiological agent of the economically most important animal disease. As a typical picornavirus, FMD virions are nonenveloped particles of icosahedral symmetry and its genome is a single stranded RNA of about 8500 nucleotides and of positive polarity. FMDV RNA is infectious and it replicates via a compleme...

Nucleotide mismatches of foot-and-mouth disease virus during replication.

As there is a lack of error correction mechanisms during RNA replication, foot-and-mouth disease virus (FMDV) has a very high mismatch rate, which leads to a high mutation rate, in the range of 10(-3) to 10(-5) per nucleotide site per genome replication. We examined the nucleotide mismatch of FMDV during replication, based on the whole genomes of the 7 serotypes retrieved from NCBI. With the Me...

pH Resistance of Foot-and-Mouth Disease Virus and its Complement-Fixing Antigen

Molecular Cloning of VPI gene of Foot-and-Mouth Disease Virus Type 01/Iran